Plasmonix is introducing products into the life science and clinical diagnostic markets that utilize Metal-Enhanced Fluorescence technology. Our QuantaWellTM, QuantArrayTM, and QuantaNPTM products deliver 10- to 1000-fold increases in fluorescent signals relative to background, which enable high-sensitivity fluorescent life science and diagnostic assays. Plasmonix’s products both improve performance of current fluorescent assays and expand the utility of fluorescence detection to assays where low-abundance targets or problematic matrices have excluded fluorescence as a viable detection method.
QuantaWell FPTM Catalog # QWFP. 96-well coated microplate delivering a 10- to 30-fold enhancement in fluorescence sensitivity in standard fluorescent polarization assays.
QuantaWell 2.0™ Catalog # QW2.0. 96-well coated microplate that delivers a 20-fold or greater fluorescence enhancement in typical fluorescence-based assays. Can be used with standard laboratory equipment and fluorescent molecules emitting in the range of 400nm – 800nm.
The figure below shows a nearly 100-fold enhanced fluorescence signal from QuantaWell 2.0 microplates compared to untreated microplates. The QuantaWell 2.0 microplates were coated with 2 µg/ml of IgG, then titrated with biotin-anti IgG which was detected with 1 µg/mL of SAPE. The sensitivity is 20-fold greater in the QuantaWell 2.0 microplates. The microplates were read in a Molecular Devices FilterMax F5 fluorometer.
The QuantaWell 2.0 is designed to be used as an alternative microplate in many conventional assays where the significant improvement in fluorescent signal delivers a real benefit to end users. We are developing assay applications with customers and collaborators and would welcome the opportunity to discuss how we might improve your assay’s performance.
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Catalog # QWFP: 5-plate pack, $150 per pack
Catalog # QW2.0: 5-plate pack, $250 per pack
Volume discounts and special one-time evaluation unit pricing are available.
Please call (410-779-9203), email (email@example.com) or fax us (410-705-6452) with your order. QuantaWell microplates will be shipped upon receipt of your Purchase Order via overnight carrier. Shipping charges are additional.
QuantArray™ Microarray Substrates. We also are well along in developing our QuantArray microarray substrates for evaluation purposes. These are microarray slides employing Plasmonix’s technology to deliver enhanced assay sensitivity of 20- to 150-fold over conventional microarray substrates. QuantArrays can be used with both DNA and protein assays and are designed to utilize current assay measurement equipment. They are particularly well suited to protein arrays where amplification alternatives are not readily available. We expect QuantaArray products to be available by April 2014.
QuantaWell 3.0™. In 2014 we expect to introduce the QuantaWell 3.0, a higher-enhancement microplate, that will at least match ELISA sensitivity and deliver improved economics and assay performance for both our business partners and end users.
QuantaNP™ Nanoparticle Reagents. Our QuantaNP products are planned for commercial introduction in 2014. The QuantaNP configuration is a direct detection reagent that delivers impressive performance that rivals that of amplification techniques — including PCR — with simpler, faster and cheaper assays.
If interested in more information or in evaluating our QuantaWell,, QuantArray or QuantaNP products, please call Plasmonix to discuss your particular assay at 410-625-5939 or email us at firstname.lastname@example.org.
Other Diagnostic Technology
Plasmonix’s technology portfolio also includes other diagnostic opportunities that utilize Metal-Enhanced Fluorescence, such as our muSystemTM platform, which adds microwave lysis and assay acceleration to deliver far more rapid and sensitive assays for the diagnosis of pathogens, STDs, biohazards and other detection applications.